Entrepreneurship education (EE) is a key economic driver aimed at stimulating economic growth, technology, innovation and business in Ghana. However, its impact on Business Startup Initiatives (BSIs) remains inadequately explored within Ghanaian Technical Universities (GTUs). In this paper, we investigated the influence of EE and Entrepreneurship courses (EC) on BSIs among business students in GTUs using the social cognitive career theory (SCCT). A survey method was used to collect data from a random sample of 320 business students in the TUs. The PLS-SEM path analysis on EE and EC had a significant positive influence on BSIs in idea generation, business plans, career choices, goals, and innovation. This study establishes the importance of EE and EC in enhancing BSIs among TU business students. This research encourages the TU management to focus on EE and the EC approaches in initiating startups. The SCCT used contributed significantly to the BSI dimensions. © 2026 Elsevier Ltd
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